Phage conversion of Shigella flexneri group antigens.

نویسندگان

  • P Gemski
  • D E Koeltzow
  • S B Formal
چکیده

A temperate phage, designated Sf6, has been isolated from Shigella flexneri 3a. Characterization of Sf6 revealed that it possesses the capacity for converting the S. flexneri 3,4 group antigen complex to group factor 6. Serological studies and chemical analysis of lipopolysaccharide from converted strains suggest that group factor 6 is a reflection of an acetylation of the preexisting 3,4 antigen complex. Evidence is provided that the 3,4 group antigen complex functions, at least in part, as a cell surface receptor site for Sf6 adsorption.

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عنوان ژورنال:
  • Infection and immunity

دوره 11 4  شماره 

صفحات  -

تاریخ انتشار 1975